99% Männliche Sexhormon Avanafil Pulver For Erectile Dysfunction
Avanafil Powder Inspection:
Avanafil Name | Avanafil |
Avanafil Also known as | Stendra, Spedr |
Avanafil CAS No | 330784-47-9 |
Avanafil Appearance | White to Off-White Cyrstalline Solid. | |
Avanafil Molecular Formula | C23H26ClN7O3 | |
Avanafil Molecular Weight | 483.95 | |
Avanafil Melting point | 150-152° C | |
Avanafil Density | 1.372 | |
Avanafil Storage | Refrigerator | |
Avanafil Usage | treatment of erectile dysfunction. Eine Phosphodiesterase 5 Inhibitor. | |
Avanafil Kategorien | Arzneimittel, API’s. Erektile Dysfunktion; Inhibitors | |
Avanafil Introduction
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by EMA and FDA, Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, while primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are vardenafil,sildenafil and tadalafil.
The advantage of avanafil is it has very fast onset of action compared with other PDE5 inhibitors, and it is absorbed quickly, reaching a maximum concentration in about 30–45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 Minuten.
Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina.Other similar drugs are tadalafil and vardenafil. Avanafil occurs as white crystalline powder, molecular formula C23H26ClN7O3 and molecular weight of 483.95 and is slightly soluble in ethanol, practically insoluble in water, and soluble in 0.1 mol/L hydrochloric acid.
Avanafil Applications:
Avanafil is a potent, highly selective phosphodiesterase 5 Inhibitor, in vitro experiments showed that the selectivity of phosphodiesterase 5 stronger than . The compound dear compliance weak against other phosphodiesterase, and effect of adenosine receptor decreased, suggesting that the cardiovascular effects of avanafil should be weaker than .
Pre clinical study showed that avanafil and organic nitrate drugs taken in combination to reduce its on blood pressure was significantly weaker than and nitrate drugs with clothes. außerdem, avanafil inhibition of phosphodiesterase 6 is very weak, the relevant visual disturbance suppression may the enzyme phosphodiesterase 5 inhibitor induced and other.
Other similar drugs are , tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors.It is absorbed quickly, reaching a maximum concentration in about 30-45 Minuten. About two-thirds of the participants were able to engage in sexual activity within 15 Minuten.
Avanafil Dose for Erectile Dysfunction:
Initial dose: 100 mg orally as needed approximately 30 minutes before sexual activity.
Maintenance dose: 50 An 200 mg orally as needed 30 minutes before sexual activity.
Maximum dose: 200 mg orally once a day
Avanafil Rezension:
-The lowest dose that provides benefit should be taken.
-Sexual stimulation is needed for a response to treatment.
-Verwendung: Treatment of erectile dysfunction