High Purity Procaine Local Anesthetic Agent Procaine Powder CAS 59-46-1
Procaine Chemical Info:
Product name: Procaine
Synonyms: Procaine; 2-(Diethylamino)ethyl 4-aminobenzoate;
CAS No.: 59-46-1
M. F.: C13H20N2O2
M. W.: 236.31
Appearance: White crystalline powder
|CAS Registry Number
||White crystalline powder
|Minimum Order Quantity
||Benzocaine, Lidocaine, Procaine, Bupivacaine, Articaine Hydrochloride
Procaine Hydrochloride vs. Procaine Base
|Product Name: Procaine Hcl, Novocain Hcl, Ethocaine Hcl.
CAS No: 51-05-8
Molecular Formula: C13H21ClN2O2
Molecular Weight: 272.77
EINECS No: 200-077-2
Appearance: white crystal or crystalline powder.
Melting point: 155-156 °C
|Other Name: Novocain, Ethocaine
Molecular Formula: C13H20N2O2
Molecular Weight: 236.31
EINECS No: 200-426-9
Procaine Hydrochloride Description:
Procaine is a kind of local anesthetics. With low toxicity but quick and safe effects, procaine is suitable for
local anesthesia, applied to the eye, ear, nose, teeth and other department operation, used for infiltration
anesthesia, anesthesia and closed therapy supervisor. Procaine is also used in the production of
procaine penicillin.Procaine is a local anesthetic. Procaine causes loss of feeling (numbness) of skin and
Procaine Hydrochloride for Local Anesthetic
Usage: Procaine hydrochloride is a kind of local anesthetics, for local anesthesia, nerve block etc, can block the conduction of nerve fibers with anesthetic effect, strong function, low toxicity, and no addiction, but the skin, mucous membrane penetration force is weak, not suitable for surface anesthesia, clinically used to infiltration, spine and conduction anesthesia.
Local anesthetic procaine hydrochloride is a local anesthetic, can block the conduction of nerve fibers with the anesthetic effect, strong function, low toxicity, and no addiction, but to the skin and mucous membrane penetration is weak, not suitable for surface anesthesia, mainly used in the clinical infiltration, spine and conduction anesthesia.
White needle crystal or crystalline powder, odorless, slightly bitter and hemp, soluble in water, soluble in ethanol, slightly soluble in chloroform, almost insoluble in ether. The ester bond structure of procaine hydrochloride can be hydrolyzed, generating p-aminobenzoic acid and two ethylamino ethanol, under certain conditions, p-aminobenzoic acid can be decarboxylated to toxic aniline.
With aromatic amino procaine hydrochloride structure, easy oxidation discoloration, pH value, temperature, ultraviolet radiation, oxygen and metal ions can be accelerated oxidation discoloration. The aqueous solution of this product is stable between pH3.0 and 5. The preparation of procaine hydrochloride injection, the general need to add acid pH3.3 ~ 5.5, and strictly control the temperature and time of sterilization, steam sterilization circulation to 100 degrees 30min is appropriate, and should pay attention to the shading, airtight preservation.
Procaine Hydrochloride Uses
Procaine is used less frequently today since more effective (and hypoallergenic) alternatives such as
lidocaine (Xylocaine) exist. Like other local anesthetics (such as mepivacaine, and prilocaine), procaine is
a vasodilator, and is thus often coadministered with epinephrine for the purpose of vasoconstriction.
Vasoconstriction helps to reduce bleeding, increases the duration and quality of anesthesia, prevents the
drug from reaching systemic circulation in large amounts, and overall reduces the amount of anesthetic
required.Unlike cocaine, a vasoconstrictor, procaine does not have the euphoric and addictive qualities
that put it at risk for abuse.
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