CAS 129453-61-8 Faslodex fulwestrant anty-nowotworowych fulwestrant octan proszku z ceną fabryczną
Drodzy klienci, Wykonujemy również standardowe fulwestrant USP, proszek, który jest nieco droższe than enterprise standard Fulwestrant.
|UWAGA:: Fulvestrant is FDA approved for the treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following anti estrogen therapy.
(1) Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive. Drugs that block the effects of these hormones can slow or stop the growth of the breast cancer cells. Fulvestrante stops oestrogen getting to the cancer cells by blocking oestrogen receptors and reducing the number of receptors the cancer cell has.
(2) Fulvestrant is a highly selective estrogen receptor antagonist. It exerts its action in the body not by targeting the production of estrogen, but by preventing it from exerting activity on the body. It does this bybinding available estrogen receptors in a competitive manner, making them unavailable for circulating estrogens. This mode of action is very similar to Nolvadex and Clomid, although unlike these two agent fulvestrant does not have mixed agonist/antagonist properties.
(3) Fulvestrant is a pure estrogen receptor antagonist. This agent also stands out as the first inject able estrogen antagonist to catch the attention of the athletic and bodybuilding world. Although not widely used here, when applied it may be effective drug for mitigating the side effects of excess estrogen caused by anabolic/androgenic steroid use such as gynecomastia, fat buildup, and increased water retention.
Fulvestrant/ Faslodex Benefits:
Fulvestrant is administered using intramuscular injections. Faslodex is liquid that is given once a month as an injection into a muscle Fulvestranthas poor oral bioavailability, it comes as a solution (liquid) in the buttockto be administeredvia intramuscular injection. Women usually get Faslodex as long as it is effectively treating the cancer.
Research has shown that Faslodex works as well as or better than Arimidex (chemical name: anastrozole), an aromatase inhibitor, in slowing or stopping the growth of metastatic (breast cancer that has spread to other parts of the body), Rak piersi z ekspresją receptorów hormonów u kobiet po menopauzie, po tamoksyfen przestał działać.