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Anti-Estrogen Raloxifene HCl SERMs Raloxifene Hydrochloride Powder
Raloxifene Hydrochloride/Raloxifene HCL Specification:
| Raloxifene Hydrochloride Name | Raloxifene Hydrochloride |
| Raloxifene Hydrochloride Alias | Raloxifene HCl |
| Raloxifene Hydrochloride CAS | 82640-04-8 |
| Raloxifene Hydrochloride Assay | 99% |
| Raloxifene Hydrochloride Molecular Formula | C28H28ClNO4S |
| Raloxifene Hydrochloride Molecular weight | 510.05 |
| Raloxifene Hydrochloride Appearance | white crystalline powder |
| Raloxifene Hydrochloride Grade | Pharmaceutical Grade |
Raloxifene Hydrochloride/Raloxifene HCL Description
Raloxifene Hcl is in a class of medications called selective estrogen receptor modulators (SERMs). Raloxifene hydrochloride acts as an anti-estrogen in both breast and uterine tissue while being estrogenic in bone. Raloxifene Hcl have efficacy against estrogen-sensitive cancers.
Raloxifene Hcl is an estrogen agonist antagonist, referred to as a selective estrogen receptor modulator and belongs to the benzothiophene class of compounds. The Raloxifene Hcl biological actions are largely mediated through binding to estrogen receptors, and it binding results in activation of estrogenic pathways in some tissues Agonism and and the blockade of estrogenic pathways in Antagonism.
Raloxifene (marketed as Evista) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer. Raloxifene hydrochloride is approved to prevent Breast cancer. It is used to decrease the chance of invasive breast cancer in postmenopausal women who have a high risk for developing the disease or who have osteoporosis.
Raloxifene Hydrochloride/Hydrochloride HCL Usage in Cancer
1) Raloxifene Hcl used to prevent & treat osteoporosis in women who have undergone menopause.
2) Raloxifene Hcl used to decrease the risk of developing invasive breast cancer in women who are at high risk of developing this type of cancer or who have osteoporosis. Raloxifene Hcl cannot be used to treat invasive breast cancer or to prevent invasive breast cancer from coming back in women who have already had the condition.
3) Raloxifene Hcl prevents and treats osteoporosis by mimicking the effects of estrogen to increase the density (thickness) of bone.
4) Raloxifene Hcl decreases the risk of developing invasive breast cancer by blocking the effects of estrogen on breast tissue, which may stop the development of tumors that need estrogen to grow.
Raloxifene Hydrochloride/Raloxifene HCL Dosage:
Raloxifene Hcl recommended initial dose is one 60 mg tablet daily. It may administered any time of day without regard to meals.
The usual adult dose is one tablet (37.5 mg) daily, administered before breakfast or 1-2 hours after breakfast. Bodybuilder dosage recommendations are consistent with those of patients, and should be individualized to obtain an adequate response with the lowest effective dose.
For some patients or bodybuilders half a tablet (18.75 mg) daily may be adequate, while others might take half a dose twice daily.
Anti Estrogen Steroids:
| Anti Estrogen Steroids | CAS No. |
| Exemestane | 107868-30-4 |
| Clomifene Citrate (Clomid) | 50-41-9 |
| Letrozole | 112809-51-5 |
| Trilostane | 13647-35-3 |
| Anastrozole | 120511-73-1 |
| Fulvestrant | 129453-61-8 |
| Tamoxifen Citrate | 54965-24-1 |
| Raloxifene Hydrochloride | 82640-04-8 |
| Flutamide | 13311-84-7 |
| Anti-estrogen Series | |
| Tamoxifen Citrate | CAS No.: 563.64 |
| Clomifene Citrate | CAS No.: 50-41-9 |
| Toremifene Citrate | CAS No.: 89778-27-8 |
| Exemestane | CAS No.: 107868-30-4 |
| Anastrozole | CAS No.: 120511-73-1 |
| Letrozole | CAS No.: 112809-51-5 |
| Fulvestrant | CAS No.: 129453-61-8 |
Raloxifene Hydrochloride/Raloxifene HCL COA:
| Test items | Specification | Test results | |
| Appearance | Yellowish powder | Comply | |
| Identification | Ir | Comply | |
| It meets the requirements of the test for choride | Comply | ||
| Solubility | Soluble in 10% sodium hydroxide solution, slightly soluble in methanol,insoluble in water | Comply | |
| Assay | 98.5%~101.5% | 99.15% | |
| Related substances | Rrt=0.74 impurity | ≤0.20% | Comply |
| Other single impurity | ≤0.10% | 0.07% | |
| Total impurities | ≤0.5% | 0.26% | |
| Loss on drying | ≤0.5% | 0.10% | |
| Residue on ignition | ≤0.1% | Comply | |
| Heavy metals | ≤10ppm | Comply | |
| Storage | Preserve in well-closed containers and protected from light.Store at room temperature. | ||
| Conclusion | Complies with usp32 standard | ||
Shipping/ Return/ Refund Policy:
| >>> Shipping Procedure: We will attempt to ship most orders within 48 hours excluding weekends or holidays.All Items are shipped safely and in manner that ensures safe arrival. If for any reason this is not the case then please email us and we will work with you. Each case is handled individually.
International and EU orders ship via Priority mail or DHL based on weight. Customer will be provided with tracking number. Shipment to countries with tropical climate will be in isolated pack and with cooling inlets. After receiving all products must be placed into refrigerator to +5° C.
>>> Resend Procedure: We will accepts returns if it is due to damage that is our fault or manufacturers defects. The items that we sell are peptide and as such could degrade if improperly handled. As a result we are unable to resell products once they have left our warehouse. The return must be within 15 days of the time of the purchase.
Peptide on the other hand, due to their fragile nature and us being to monitor how they were handled when they were out of care, could possibly degrade. We prefer not to accept returns of peptide due to this fact.If you are missing an item or the item you receive is damaged, then please contact us and we will sent out a replacement free of shipping cost to you.
>>> Delivery Insurance: All our shipments are insured. We guarantee delivery regardless of any obstacles that might happen on the way. None of our customers have ever been left empty handed and neither will you. |
